' 
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
USERS' SCORE
Good
Based on 3 Reviews
8.6
Supplement Facts
Serving Size: 4 Capsules
Serving Per Container: 30
Amount Per Serving
%DV
Vitamin C (from culture of S. cerevisiae)
50 mg
56%
Vitamin D (as D3 from culture of S. cerevisiae)
40 mcg (1,600 IU)
200%
Vitamin K (from culture of S. cerevisiae)
120 mcg
100%
Calcium (naturally occurring from Algae)
1,100 mg
85%
Magnesium (from Algae and Dead Sea minerals)
357 mg
85%
Vitamin K (as K2 MK-7)
50 mcg
+
Strontium (naturally occurring from Algae)
3.8 mg
+
Boron (from Brown Rice Chelate)
3 mg
+
Silica (naturally occurring from Algae)
2.2 mg
+
Vanadium (naturally occurring from Algae)
25 mcg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU).
64 mg
+
Top Medical Research Studies
9.5
Vitamin D benefits IBS patients
The efficacy of vitamin D supplementation for irritable bowel syndrome: a systematic review with meta-analysis.
Direct effect on IBS explored
We examined how vitamin D supplementation could help improve symptoms for those suffering from irritable bowel syndrome (IBS). This systematic review pulled together findings from four randomized, placebo-controlled trials, with a total of 335 participants, to determine the effectiveness of vitamin D on various IBS measures.
Participants with IBS often struggle with symptoms like pain and discomfort, and vitamin D deficiency has been frequently noted in these individuals. Our research indicated that taking vitamin D could lead to significant improvements in IBS severity compared to a placebo. The results showed that those receiving vitamin D reported notable changes in their IBS severity scores and quality of life scores after the supplementation.
Specifically, after taking vitamin D, participants fared much better in terms of symptom relief than those who received a placebo. While we found some variability in the overall effects on the total score of IBS, the positive outcomes in severity and quality of life were compelling. Overall, our findings suggest that vitamin D supplementation presents a promising option for managing IBS symptoms.
Participants with IBS often struggle with symptoms like pain and discomfort, and vitamin D deficiency has been frequently noted in these individuals. Our research indicated that taking vitamin D could lead to significant improvements in IBS severity compared to a placebo. The results showed that those receiving vitamin D reported notable changes in their IBS severity scores and quality of life scores after the supplementation.
Specifically, after taking vitamin D, participants fared much better in terms of symptom relief than those who received a placebo. While we found some variability in the overall effects on the total score of IBS, the positive outcomes in severity and quality of life were compelling. Overall, our findings suggest that vitamin D supplementation presents a promising option for managing IBS symptoms.
Read More
9
Vitamin D improves IBS management
Impact of vitamin D supplementation on symptom severity and quality of life in patients with irritable bowel syndrome: A meta-analysis.
Highly relevant IBS treatment insights
We aimed to find out how vitamin D supplementation might help those suffering from irritable bowel syndrome (IBS). To do this, we conducted a thorough review of nine randomized controlled trials that included a total of 780 participants.
Our findings showed that vitamin D supplementation significantly improved IBS symptoms and overall quality of life. Specifically, we observed a notable reduction in symptom severity scores and increased satisfaction with life among those taking vitamin D compared to those who did not. Additionally, we confirmed an increase in the levels of serum 25(OH)D, which is crucial for overall health.
Importantly, we also found that the risks of any adverse events while taking vitamin D were low. The results suggest that vitamin D could be a promising option for managing IBS effectively and safely.
Our findings showed that vitamin D supplementation significantly improved IBS symptoms and overall quality of life. Specifically, we observed a notable reduction in symptom severity scores and increased satisfaction with life among those taking vitamin D compared to those who did not. Additionally, we confirmed an increase in the levels of serum 25(OH)D, which is crucial for overall health.
Importantly, we also found that the risks of any adverse events while taking vitamin D were low. The results suggest that vitamin D could be a promising option for managing IBS effectively and safely.
Read More
8
Vitamin D's effect on IBS
Causal associations of 25-hydroxyvitamin D with functional gastrointestinal disorders: a two-sample Mendelian randomization study.
Focuses on vitamin D and IBS
We set out to investigate how vitamin D levels, particularly serum 25-hydroxyvitamin D, might affect the risk of developing irritable bowel syndrome (IBS). Using a sophisticated approach called Mendelian randomization, we analyzed data collected from large biobanks. This method allows us to draw more robust conclusions about causality, especially given the controversies surrounding previous observational studies.
Our analysis focused on a substantial number of participants and examined the genetic factors associated with both vitamin D levels and IBS. While we found no significant causal relationship between vitamin D intake and IBS, we discovered an intriguing result regarding 25-hydroxyvitamin D. Specifically, higher levels of this form of vitamin D seemed to correlate with a decreased risk of IBS. More precisely, each additional standard deviation increase in genetically determined 25-hydroxyvitamin D was linked to a 16.8% lower risk of developing IBS.
Nevertheless, it's important to acknowledge the complexity of these findings. Although we observed a negative causal relationship between 25-hydroxyvitamin D and IBS, the same could not be said for vitamin D intake or functional dyspepsia (FD). This study brushes against the broader conversation about the potential health benefits of vitamin D while acknowledging that further research is necessary to fully understand these dynamics.
Our analysis focused on a substantial number of participants and examined the genetic factors associated with both vitamin D levels and IBS. While we found no significant causal relationship between vitamin D intake and IBS, we discovered an intriguing result regarding 25-hydroxyvitamin D. Specifically, higher levels of this form of vitamin D seemed to correlate with a decreased risk of IBS. More precisely, each additional standard deviation increase in genetically determined 25-hydroxyvitamin D was linked to a 16.8% lower risk of developing IBS.
Nevertheless, it's important to acknowledge the complexity of these findings. Although we observed a negative causal relationship between 25-hydroxyvitamin D and IBS, the same could not be said for vitamin D intake or functional dyspepsia (FD). This study brushes against the broader conversation about the potential health benefits of vitamin D while acknowledging that further research is necessary to fully understand these dynamics.
Read More
Most Useful Reviews
8.8
Regulates bowel movements
I find this calcium great; my body responds well to it. I take just two a day due to my small frame, and it also helps with my bowel regularity. Taking too much can make things overly frequent.
Read More
8.8
Essential for IBS
This product has become essential for me. I initially chose it for its low calcium content, but it has also greatly improved my bowel movements during the four years I’ve been using it.
Read More
8.8
Improves IBS symptoms
This is a good source of calcium and vitamin D, paired with probiotics and enzymes that enhance my bowel movements. It has helped manage my irritable bowel syndrome effectively.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 18 Researches
7.6
9.5
Vitamin D benefits IBS patients
The efficacy of vitamin D supplementation for irritable bowel syndrome: a systematic review with meta-analysis.
Direct effect on IBS explored
We examined how vitamin D supplementation could help improve symptoms for those suffering from irritable bowel syndrome (IBS). This systematic review pulled together findings from four randomized, placebo-controlled trials, with a total of 335 participants, to determine the effectiveness of vitamin D on various IBS measures.
Participants with IBS often struggle with symptoms like pain and discomfort, and vitamin D deficiency has been frequently noted in these individuals. Our research indicated that taking vitamin D could lead to significant improvements in IBS severity compared to a placebo. The results showed that those receiving vitamin D reported notable changes in their IBS severity scores and quality of life scores after the supplementation.
Specifically, after taking vitamin D, participants fared much better in terms of symptom relief than those who received a placebo. While we found some variability in the overall effects on the total score of IBS, the positive outcomes in severity and quality of life were compelling. Overall, our findings suggest that vitamin D supplementation presents a promising option for managing IBS symptoms.
Participants with IBS often struggle with symptoms like pain and discomfort, and vitamin D deficiency has been frequently noted in these individuals. Our research indicated that taking vitamin D could lead to significant improvements in IBS severity compared to a placebo. The results showed that those receiving vitamin D reported notable changes in their IBS severity scores and quality of life scores after the supplementation.
Specifically, after taking vitamin D, participants fared much better in terms of symptom relief than those who received a placebo. While we found some variability in the overall effects on the total score of IBS, the positive outcomes in severity and quality of life were compelling. Overall, our findings suggest that vitamin D supplementation presents a promising option for managing IBS symptoms.
Read More
9
Vitamin D improves IBS management
Impact of vitamin D supplementation on symptom severity and quality of life in patients with irritable bowel syndrome: A meta-analysis.
Highly relevant IBS treatment insights
We aimed to find out how vitamin D supplementation might help those suffering from irritable bowel syndrome (IBS). To do this, we conducted a thorough review of nine randomized controlled trials that included a total of 780 participants.
Our findings showed that vitamin D supplementation significantly improved IBS symptoms and overall quality of life. Specifically, we observed a notable reduction in symptom severity scores and increased satisfaction with life among those taking vitamin D compared to those who did not. Additionally, we confirmed an increase in the levels of serum 25(OH)D, which is crucial for overall health.
Importantly, we also found that the risks of any adverse events while taking vitamin D were low. The results suggest that vitamin D could be a promising option for managing IBS effectively and safely.
Our findings showed that vitamin D supplementation significantly improved IBS symptoms and overall quality of life. Specifically, we observed a notable reduction in symptom severity scores and increased satisfaction with life among those taking vitamin D compared to those who did not. Additionally, we confirmed an increase in the levels of serum 25(OH)D, which is crucial for overall health.
Importantly, we also found that the risks of any adverse events while taking vitamin D were low. The results suggest that vitamin D could be a promising option for managing IBS effectively and safely.
Read More
9
Probiotic effects on IBS symptoms
Effects of 35624 in Children and Adolescents with Irritable Bowel Syndrome.
No specific vitamin D effects
We conducted a study to understand how probiotic 35624 affects irritable bowel syndrome (IBS) in children and adolescents aged 8 to 18. This real-world study, carried out in Chile, involved 64 young participants over a span of 12 weeks, during which we closely monitored their gastrointestinal symptoms.
Throughout the study, participants showed significant improvements in various IBS symptoms measured by specific scoring systems. By week 6 and again at week 12, we saw strong positive changes with 98.3% of them experiencing improvements in three or more IBS domains. This shift was impressive, as the severity of their IBS symptoms moved from moderate or severe to mild or in remission.
Interestingly, the study also looked into vitamin D levels, as vitamin D deficiency is prevalent among children in Latin America. However, we found that low baseline serum vitamin D levels did not correlate with the severity of IBS symptoms or the response to the probiotic treatment. While the improvements were promising, they did not last after a two-week washout period, highlighting the need for more research to understand these effects fully, particularly regarding vitamin D's influence.
Throughout the study, participants showed significant improvements in various IBS symptoms measured by specific scoring systems. By week 6 and again at week 12, we saw strong positive changes with 98.3% of them experiencing improvements in three or more IBS domains. This shift was impressive, as the severity of their IBS symptoms moved from moderate or severe to mild or in remission.
Interestingly, the study also looked into vitamin D levels, as vitamin D deficiency is prevalent among children in Latin America. However, we found that low baseline serum vitamin D levels did not correlate with the severity of IBS symptoms or the response to the probiotic treatment. While the improvements were promising, they did not last after a two-week washout period, highlighting the need for more research to understand these effects fully, particularly regarding vitamin D's influence.
Read More
9
Probiotics and Vitamin D help IBS
Probiotics plus vitamin D in irritable bowel syndrome: a prospective multicentric non-interventional study.
Combination treatment evaluated effectively
We investigated the impacts of a combination treatment involving probiotics and vitamin D on individuals with irritable bowel syndrome (IBS), specifically those experiencing diarrhea-predominant IBS (IBS-D) or mixed bowel movements (IBS-M). The study involved 246 adults followed by private gastroenterologists, who were given a daily dose of probiotics along with vitamin D over a period of 42 days.
At the end of this timeframe, we found that a significant number of patients—about 62.9%—reported improvements in their symptoms. In fact, there was a notable decrease in the IBS Severity Scoring System scores. This improvement also correlated with enhancements in overall quality of life related to IBS, as well as reductions in anxiety and depression symptoms.
Our findings align with earlier randomized clinical trials, reinforcing the notion that the probiotic and vitamin D combination can be beneficial. While we recognize that this study consolidates the evidence of such a combination rather than isolating the effects of vitamin D alone, the results suggest that including vitamin D in treatment plans may indeed foster better mental and gut health for those suffering from IBS.
At the end of this timeframe, we found that a significant number of patients—about 62.9%—reported improvements in their symptoms. In fact, there was a notable decrease in the IBS Severity Scoring System scores. This improvement also correlated with enhancements in overall quality of life related to IBS, as well as reductions in anxiety and depression symptoms.
Our findings align with earlier randomized clinical trials, reinforcing the notion that the probiotic and vitamin D combination can be beneficial. While we recognize that this study consolidates the evidence of such a combination rather than isolating the effects of vitamin D alone, the results suggest that including vitamin D in treatment plans may indeed foster better mental and gut health for those suffering from IBS.
Read More
9
Vitamin D may relieve IBS symptoms
Role of 25-hydroxyvitamin D in irritable bowel syndrome patients.
Strong study relevance for IBS treatment
We aimed to understand how vitamin D treatment affects individuals with irritable bowel syndrome (IBS) who didn’t have any identifiable stressors contributing to their symptoms. For this study, we provided vitamin D supplements to patients over a three-month period. Of the patients, 97 had their vitamin D levels checked again, showing sufficient improvement, while 14 were lost to follow-up.
Our approach suggested that intramuscular injections were the best form of treatment, but interestingly, we found that 34 of the participants opted for oral supplements. Those taking oral vitamin D displayed a lesser increase in serum vitamin D levels compared to those receiving injections.
The results were promising: over half, specifically 56.7%, reported complete relief from their IBS symptoms after vitamin D replacement. Additionally, 36.1% experienced significant improvement, and 6.2% noted moderate relief. The study also highlighted that even though many found relief, we need to consider the 14 individuals lost to follow-up when interpreting the overall effectiveness.
Our approach suggested that intramuscular injections were the best form of treatment, but interestingly, we found that 34 of the participants opted for oral supplements. Those taking oral vitamin D displayed a lesser increase in serum vitamin D levels compared to those receiving injections.
The results were promising: over half, specifically 56.7%, reported complete relief from their IBS symptoms after vitamin D replacement. Additionally, 36.1% experienced significant improvement, and 6.2% noted moderate relief. The study also highlighted that even though many found relief, we need to consider the 14 individuals lost to follow-up when interpreting the overall effectiveness.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.6
8.8
Regulates bowel movements
I find this calcium great; my body responds well to it. I take just two a day due to my small frame, and it also helps with my bowel regularity. Taking too much can make things overly frequent.
8.8
Essential for IBS
This product has become essential for me. I initially chose it for its low calcium content, but it has also greatly improved my bowel movements during the four years I’ve been using it.
8.8
Improves IBS symptoms
This is a good source of calcium and vitamin D, paired with probiotics and enzymes that enhance my bowel movements. It has helped manage my irritable bowel syndrome effectively.
